Copper Storage Disease in Dogs

Cost of Treatment: $100 to $1,000 for ongoing monthly medication

What it is: Also called hepatotoxicosis, copper storage disease is a genetic liver disorder caused by a buildup of copper in the dog’s liver. Certain breeds are predisposed to the condition, unable to eliminate copper from their livers.


  • Weakness and lethargy
  • Weight loss and anorexia
  • Vomiting
  • Dehydration
  • Bloody stool
  • Depression

Treatment:Treatment typically involves copper chelation, which is a type of drug therapy that binds copper before it enters the liver. IV fluids, vitamins and other medications may also be used in a treatment plan. Depending on the medications used, chelation drugs can run upwards of several hundred dollars per month for the lifetime of your dog. Many dog insurance plans cover the cost of prescription medications and other costs associated with copper storage disease treatment.

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